| PleraSAN®
is safe and effective either taken orally or applied topically.
ORALLY:
1. PleraSAN® travels through the digestive
system and reaches the small intestine. Being indigestible it
is not broken down by the body, thereby maintaining its natural
structure necessary for its immuno-modulating activity.
2. In the small intestine it reaches Peyer's patches. These
are nodules with a high concentration of immune cells.
3. Immune cells in the Peyer's patch can easily detect PleraSAN®
as receptors on the surface of these are especially sensitive
to its presence.
4. Once immune cells detect the presence of PleraSAN®
they are "convinced" that a pathogen has entered the
body and begin a cascade of immune activities against viral,
bacterial, fungal and parasitic infections.
TOPICALLY:
 Topically,
PleraSAN® activates keratinocytes and specialised
immune cells of the skin, called Langerhans Cells (LC) found
in the epidermis.
Keratinocytes,
the most common type of skin cell,
are activated by PleraSAN®, which then
communicate to other skin cells using cytokines.
The
release of cytokines activates immune responses and skin regeneration
processes
LCs
are the most important immune cells of the skin responsible
for identifying and transporting antigens to the lymph node.
LCs play an important role in skin regeneration and healing
processes.
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